New Carlisle is part of Michiana, an area that encompasses Northwest Indiana surrounding South Bend and vicinity and Southwest Michigan. New Carlisle is located approximately 4 miles south of the Indiana/Michigan state line, between South Bend and Lake Michigan on State Route 20, also know as The historic "Lincoln Highway". It is accessable from Interstate 80/90 via bypass State Route 31, State Route 2 from South Bend, or State Route 20 from Michigan City.
A "South Shore Line" commuter station connecting Chicago and South Bend is located in nearby Hudson Lake. Amtrak stations are located in South Bend and New Buffalo, Michigan. The South Bend International Airport is a fifteen minute drive from downtown New Carlisle. Downtown Chicago is a ninety minute drive via Interstate 80/90 (The Indiana Tollway), or Interstate 94.
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